Apple Leaves Extract Phloretin for Whitening Agents Lighten Spot 60-82-2

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Delivery term: The date of payment from buyers deliver within days
seat: Shaanxi
Validity to: Long-term effective
Last update: 2018-03-19 04:44
Browse the number: 132
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Product details

Apple Leaves Extract Phloretin for Whitening Agents Lighten Spot


Product introduction

Phloretin is a dihydrochalcone compound, is a new natural skin whitening agent, mainly distributed in apples and other juicy fruit peel and root bark. Phloretin has a weak estrogen activity.


Product parameter

 Phloretin

Trade Name: Shaanxi Huatai Bio-fine Chemical Co., Ltd.

Common Name: Phloretin

Chemical Name : 2',4',6'-TRIHYDROXY-3-(4-HYDROXYPHENYL)PROPIOPHENONE

CAS No.: 60-82-2

EINECS No.: 200-488-7

Molecular Formula: C15H14O5

Molecular Structure:                

Characteristics: White powder

Solubility: Dissolved in ethanol, 1,3-butanediol. Do not dissolved in water

Specification: Cosmetic grade

Category: Skin Care

Features: The Studies have shown that phloretin can inhibiting melanocytes, inhibiting tyrosinase activity, and has effects on various skin pigmentation. Phloretin also has Anti-inflammatory and immunosuppressive effects. Research showed that cause the phloretin, NO release volume of macrophage was significantly decreased under the stimulation of lipopolysaccharide (LPS) and IFN-γ.

Typical Dosage: 3‰-5‰

Packing: 1kg aluminum foil bag

Transport: Non-hazardous cargo(IMO/IATA)

Remarks: Safety and efficacy report available upon request.


Product feature application

Anti-inflammatory and immunosuppressive effects. Research showed that cause the phloretin, NO release volume of macrophage was significantly decreased under the stimulation of lipopolysaccharide (LPS) and IFN-γ. Phloretin has a potential anti-inflammatory effect. In immunosuppression, studies have shown that phloretin has a significant inhibitory effect on mouse T lymphocyte activation.

Phloretin induced cytotoxicity on lymphocytes N=6, *±S.control

Group

Dose/μmol·L-1

A

Survival rate/%

Negative




Control


0.140±0.002

/

Positive




Control


0.365±0.007

100

Phloretin

40

0.332±0.013

88.87


60

0.316±0.021

81.48


80

0.297±0.015

72.68

Figure :Proliferation of lymphocytes analyzed by CFSE-labelling (n = 4, x ± s).


Product qualification

Deliver, shipping and serving

Applications: Widely used in cosmetic product as cream, paste, water solution and emulsion.


1. 1kg with double plastic container inside/Aluminum foil bag outside.
2. 25kg with double plastic container inside/Fiber drum outside.
3. The final decision will be made by your company.

http://www.natural-ingredient.com/

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